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Fig. 7 | Genome Biology

Fig. 7

From: Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing

Fig. 7

Inferred RNA maps for selected RBPs. To create this plot, we performed in silico knockdowns on the binarized version of our model and measured changes to splicing. We then aggregated across several positions to create overall effects at each position in the meta-exon. The results here are normalized for each motif individually, with an absolute value of 1 corresponding to the 99th percentile across positions. This normalization enables us to see the RNA map for each motif. The x-axis here is in two parts, with the left half being relative to 3′ sites (A) and the right half being relative to 5′ sites (D); a schematic exon is shown at bottom

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