Fig. 6
From: ChIPr: accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features
ChIPr captures majority of cell-type-dependent interactions and Hi-C identified loops. A Original interactions and predicted ones for the four cell lines GM12878, K562, H1, and HepG2 using the three variants of ChIPr in the region surrounding the MYC oncogene. Interactions shown are those having strength ≥ “3”. Red: original loops from RAD21 ChIA-PET data; blue: predicted loops by ChIPr. B–D Predicted interactions using DNN-ChIPr (B), RF-ChIPr (C), and GB-ChIPr (D) captured the majority of the Hi-C identified loops captured by the original ChIA-PET data from the cell lines GM12878 and K562