Fig. 3
From: From beer to breadboards: yeast as a force for biological innovation
Left: An overview of genetic and chemical–genetic interactions in yeast compiled from diverse large-scale data sources, including SGA, PPI, and chemogenomics (left panel). The right panel shows a higher resolution representation of gene–gene and gene–drug interactions as they relate to diverse cellular processes. Genes are visualized as circular nodes, while the interactions between them are depicted as lines connecting these nodes. It shows the genetic interactions for the ERO1 module comprising a network of genes with shared genetic interactions, some of which are shared by the chemical–genetic interaction network induced by treatment with Erodoxin, a small molecular Ero1 inhibitor whose structure is illustrated