Skip to main content
Fig. 2 | Genome Biology

Fig. 2

From: SURGE: uncovering context-specific genetic-regulation of gene expression from single-cell RNA sequencing using latent-factor models

Fig. 2

SURGE applied to GTEx v8 bulk RNA-seq samples. A, B SURGE latent context loadings of GTEx v8 RNA-seq samples (y-axis) stratified by A known tissue identity and B known ancestry for top 8 inferred SURGE latent contexts. C Scatter plot of SURGE latent context 2 loadings (x-axis) and xCell Epithelial cell type enrichment score (y-axis) for GTEx v8 RNA-seq samples colored by known tissue identity (same color palette as A). D GTEx v8 RNA-seq samples are separated into 10 quantile bins according to their value on SURGE latent context 6. The stacked bar plot depicts the average xCell cell type enrichment scores across all samples normalized to sum to 1 (y-axis) in each of the 10 bins (x-axis)

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us