Fig. 8From: RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9Model for the new regulatory axis RBM5-HOXA9 in AML. RBM5 directly regulates the transcriptional activity of the HOXA9 locus, which maintains proper downstream signaling transduction, including the FLT3-responsive targets in acute myeloid leukemia cellsBack to article page