Fig. 5

Spatially variable gene detection performance across 9 simulated datasets. a Scatter plot of observed true positive rate (y-axis) and false discovery rate (x-axis) of spatially variable gene detection by the benchmarked tools at six adjusted p-value cut-offs at 0.1, 0.01, and 0.05. Each dot is color-coded by the cut-off used. The two horizontal lines represent the true FDRs of 0.01 and 0.05. b The proportion of ground truth SVGs among significant SVGs determined by each method at an FDR-adjusted p-value of 0.01