Fig. 6

Prioritize HC ELEs for schizophrenia. Legends of a, b are the same as those in Fig. 5a, b. c Schizophrenia associations of 26 HC ELEs that contain instances of the enriched motif TCTTATGCTT. d Schizophrenia associations of 27 HC ELEs that contain instances of the enriched motif SGTTCTGGTT. For c, d, the rest is the same as Fig. 5c, d. e Overlap of the putative target genes (59 for TCTTATGCTT-instance and 59 for SGTTCTGGTT-instance HC ELEs) with genes implicated in knockout mouse phenotypes. f, g Putative target genes of schizophrenia-associated HC ELEs with the enriched motif SGTTCTGGTT that cause neural, cardiac, or both types of knockout mouse phenotypes (f) and neural, cardiac, or both types of human Mendelian traits (g). For f, g, genes shown in bold font are implicated in both knockout mouse phenotypes and human Mendelian traits