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Fig. 2 | Genome Biology

Fig. 2

From: The hazards of genotype imputation when mapping disease susceptibility variants

Fig. 2

Locations of the imputed SNPs in relation to the T2D locations and surrounding haplotypes. The tables for the a) ACTL7B, b) KCNK3 and c) TCF7L2 regions give the frequencies of the haplotypes using all ♦scaffold and ♦T2D-associated (imputed) SNPs with their risk alleles in bold. The white bars within the tables represent other allelic differences between the haplotypes. The T2D locations, A and E were estimated [5] from African-American (AA) and European (EUR) data and mapped onto the respective LDU maps (linkage disequilibrium distances on Y axis). The published GWAS lead SNP (rs7903146) for TCF7L2 is also plotted in Fig. 1c

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