Fig. 7

Prediction of expression levels of unmeasured genes for STARmap. a Predicted expression patterns of five unmeasured genes (top) and their ISH images (bottom). b Known patterns in STARmap. The first row shows the expression levels of known patterns, averaged by measured genes. The second row presents expression levels averaged by unmeasured genes. The number of genes within each pattern is listed. The third row showcases representative unmeasured genes and their corresponding ISH images. These patterns co-localize with distinct cell types (bottom). c Multimodality structure of likelihood scores of unmeasured genes. These genes can be divided into three categories using dashed lines at s ± 0.05, where s (blue point) represents the likelihood score at the low peak between two high peaks. d Discovery of three novel patterns in STARmap. The first row illustrates the expression levels of three novel patterns, along with the number of genes constituting each pattern. The second row displays representative genes and their corresponding ISH images. These novel patterns demonstrate co-localization with different cell types (bottom). e Functional enrichment analysis. Functional enrichment results are provided (top six) for the three novel patterns