Methylation-directed regulatory networks determine enhancing and silencing of mutation disease driver genes and explain inter-patient expression variation

Table 1 Mutated driver genes per tumor

Tumors with 5 or more mutations are in bold
na data not available
-, not detected
^aCoding-sequence alternation
^bCoding-copy-number alternations
^cRegulatory-sequence alternation
^dRegulatory-copy-number alternations
^eNumbers of abnormally expressed (twofold or more expression differences from normal brain samples) driver genes for which methylation alternations describe their expression-variation
^fNumbers of abnormally expressed driver genes for which methylation alternations were the only type of mutation

ISSN: 1474-760X