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Fig. 5 | Genome Biology

Fig. 5

From: Dual spatially resolved transcriptomics for human host–pathogen colocalization studies in FFPE tissue sections

Fig. 5

Colocalization analysis reveals human host response to SARS-CoV-2 infection. a Dot plot depicting differential expression of human genes in SARS-CoV-2+ and SARS-CoV-2- spots in COVID-19 sections. b Spatial distribution of RNase1, downregulated in SARS-CoV-2+ spots, and CXCL9, upregulated in SARS-CoV-2+ spots, in COVID-19 sample 1C. Scale bars are 500 µm. Differential expression analysis used the Wilcoxon rank sum test and DESeq2 negative binomial distribution tests, p-value < 0.05

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Genome Biology

ISSN: 1474-760X

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