Fig. 1
From: MCProj: metacell projection for interpretable and quantitative use of transcriptional atlases
Human cell bone marrow atlas. This atlas was computed using the Metacells-2 algorithm and was used as a basis for the analysis below. A Heatmap of feature gene expression in the atlas metacells. Annotated cell types are color coded at the top. B 2D UMAP projection of the atlas metacells. Edges are visualizing a metacell similarity graph. C Quantitative gene expression comparison over metacells, shown for select genes that were defined as essential for a cell type annotation