Fig. 3From: GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membershipGoM DE analysis of the PBMC data using the topic model shown in Fig. 1. The volcano plots show posterior mean estimates of the l.e. LFC vs. posterior z-scores for 17,055 genes. The posterior z-score is defined as the posterior mean l.e. LFC divided by the posterior standard error. Genes are colored according to the local false sign rate (lfsr) [82]. A few genes with extreme posterior z-scores are shown with smaller posterior z-scores so that they fit within the y-axis range. See also the detailed GoM DE results (Additional file 2: Table S1), detailed GSEA results (Additional file 3: Table S3, S4), and the interactive volcano plots (Additional file 4)Back to article page