From: Genomic variant benchmark: if you cannot measure it, you cannot improve it
Technology | Company | Device name | Read length (bp) | Input DNA (microgram) | Cost | Sequencing time (hour) |
---|---|---|---|---|---|---|
Sequencing by synthesis | Illumina | NovaSeq 6000 | 100–300 | 0.3e | $ | 44d |
Single Molecule Real-Time | PacBio | Sequel IIE | ~ 15 k | 5b | $$$ | 30c |
Nanopore | ONT | PromethION | Up to 4 m | 30f | $$ | 60 |
Tell-seq | Universal Sequencing Technology | TELL-Seq Library Prep Kit | 100 k range information | 5ngg | $i + Illumina cost | 3 + Illumina run |
Illumina Complete Long-Read technology (previously announced as “Infinity”) | Illumina | N/A | Up to 10 k | 50ngj | $ | N/A |
AVITI | Element | Element AVITI System | 2*150 or 10 k | 0.1–0.5 | $ | 48a |
Ultima | Ultima Genomics | UG 100 | 300 | 0.25 | $h | 20 |
Sequencing by binding | PacBio (formerly Omniome) | N/A | 200 | N/A | N/A | N/A |