HycDemux: a hybrid unsupervised approach for accurate barcoded sample demultiplexing in nanopore sequencing

Table 6 Performance of HycDemux and Guppy (GPU version) on D1\(\sim\)D7 with a 10\(\sim\)15% sequencing error rate

Dataset	Minimum accuracy		Average accuracy		Recall		Unclassified		Run time (m:s)
Dataset	Guppy	HycDemux	Guppy	HycDemux	Guppy	HycDemux	Guppy	HycDemux	Guppy	HycDemux
D1	0.9940	0.9820	0.9990	0.9905	0.9990	0.9899	1012	1109	0:08	0:17
D2	0.9880	0.9840	0.9972	0.9918	0.9971	0.9919	1066	1146	0:24	0:54
D3	0.9740	0.9530	0.9961	0.9892	0.9960	0.9894	1330	1604	4:31	7:18
D4	0.6170	0.9620	0.9554	0.9898	0.9552	0.9897	9732	2616	5:15	12:07
D5	0.4150	0.9430	0.9519	0.9872	0.9518	0.9871	12,794	3208	8:01	19:54
D6	0.4150	0.9450	0.9516	0.9895	0.9514	0.9894	15,253	3443	11:19	25:15
D7	0.4150	0.9260	0.9489	0.9902	0.9488	0.9901	18,623	3565	15:19	33:49

ISSN: 1474-760X