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Table 3 Read cloud summary statistics. For Ariadne deconvolution, we used a search distance of 5 kbp. The 3-5th columns contain the average and standard deviations of read cloud statistics. Prop. Under, Comp., and Over refer to the proportion of total original or deconvolved read clouds that were over- or under-deconvolved, or completely and exactly comprised of all of the reads from a single inferred genomic fragment

From: Ariadne: synthetic long read deconvolution using assembly graphs

Dataset

Deconv. Method

Avg. Purity

Avg. Entropy

Avg. Size

Num. clouds

Prop. Under

Prop. Comp.

Prop. Over

MOCK5 10x

None

0.53 ± 0.16

1.61 ± 0.52

63.51 ± 51.64

1 425 430

0.98

0.02

0

MOCK5 10x

Reference

0.99 ± 0.05

0.03 ± 0.14

18.47 ± 19.26

4 733 136

0.06

0.91

0.03

MOCK5 10x

Ariadne

0.89 ± 0.22

0.37 ± 0.7

12.18 ± 15.26

4 753 473

0.25

0.04

0.71

MOCK5 LoopSeq

None

0.93 ± 0.11

0.31 ± 0.31

269.18 ± 356.67

276 665

0.68

0.32

0

MOCK5 LoopSeq

Reference

0.98 ± 0.07

0.06 ± 0.21

116.19 ± 252.59

637 012

0.14

0.82

0.04

MOCK5 LoopSeq

Ariadne

0.88 ± 0.21

0.4 ± 0.7

101.44 ± 225.71

734 143

0.35

0.14

0.51

MOCK20 10x

None

0.38 ± 0.15

2.28 ± 0.62

186.49 ± 129.32

503 205

0.97

0.03

0

MOCK20 10x

Reference

0.99 ± 0.06

0.05 ± 0.18

29.31 ± 29.26

3 146 784

0.13

0.83

0.04

MOCK20 10x

Ariadne

0.94 ± 0.18

0.22 ± 0.64

13.56 ± 22.69

6 920 196

0.13

0.05

0.83

MOCK20 TELL-Seq

None

0.39 ± 0.15

2.37 ± 0.59

160.45 ± 110.51

623 026

0.98

0.02

0

MOCK20 TELL-Seq

Reference

1 ± 0.02

0 ± 0.05

23.83 ± 27.65

4 067 621

0.01

0.99

0

MOCK20 TELL-Seq

Ariadne

0.87 ± 0.24

0.47 ± 0.89

21.96 ± 30.74

4 074 321

0.25

0.04

0.71