Fig. 3
From: SEESAW: detecting isoform-level allelic imbalance accounting for inferential uncertainty
SEESAW results for the mouse osteoblast differentiation dataset (TSS-level analysis). AÂ Global AI results for the gene Fuca2 where TSS groups showed discordant direction of imbalance. The computed statistics are plotted directly below the TSS group. B6 refers to the strain of C57BL/6J and CAST refers to the strain of CAST/EiJ, each parents in the F1 cross. Isoform proportion per TSS group was calculated by summing the estimated TPM (transcript per million) of the isoforms in the group and dividing by the gene-level TPM. Allelic proportion was calculated by dividing estimated allelic counts for each strain by the total counts from both alleles. BÂ Dynamic AI revealed for two TSS groups of Rasl11b. Estimation uncertainty shown with error bars (95% intervals based on bootstrap variance)