Fig. 5

vLADs are associated with gene ontologies consistent with induction of adipogenic differentiation. a Gene ontology terms (PANTHER biological process) associated with all protein-coding genes found in “Lost LAD” and “Lost edge” LAD classes. See Additional file 1, Table S6 for GO term summaries in all LAD classes. b Expression z-scores of all expressed protein-coding genes in LAD classes shown in a, at T00, T24, and T72. Bar, median; cross, mean; box, 25–75 percentile, whiskers min-max; *P = 0.04, unpaired two-tailed t-test with Welch’s correction. c Genome browser views of LADs and mRNA levels (read count scales shown in brackets) for indicated DE genes; note that LADs extend beyond the areas shown. d Numbers of adipogenic genes (GSEA Hallmark_Adipogenesis) in LADs and i-LADs in undifferentiated (T00) ASCs