Fig. 4
From: TraSig: inferring cell-cell interactions from pseudotime ordering of scRNA-Seq data
Ligand-receptor interaction predictions from TraSig of interest for functional studies. a Cartoon of cell signaling interaction between different DesLO cell types (HLC, hepatocyte-like cells; CLC, cholangiocyte-like cells; SLC, stellate-like cells; ELC, endothelial-like cells). b Trajectory plot showing cell type assignments with key identifying genes highlighted by different colors (red = SOX2+ non-induced cells, yellow = SOX9 cholangiocyte-like cells, blue = hepatocyte-like cells, purple = stellate-like cells, green = endothelial-like cells). c Sender CXCL12 cells from the cholangiocyte and stellate populations in red shown with the receiver CXCR4 expressing endothelial cell population in blue. d Sender and receiver signaling populations (red = senders/ligands; blue = receivers/receptors). The darker the color is, the higher the expression level in a cell