Table 1 Overview of modelled features for the compared simulators
From: ReSeq simulates realistic Illumina high-throughput sequencing data
| Â | ART | pIRS | NEAT | BEAR | ReSeq |
|---|---|---|---|---|---|
Coverage | Parameters | Parameters | Parameters | Parameters | Mapped reads/ Parameters |
GC bias | – | Mapped reads | Mapped reads | – | Mapped reads |
Flanking bias | – | – | – | – | Mapped reads |
Fragment length | Parameters | Parameters | Mapped reads | Parameters | Mapped reads |
Reference-sequence bias | – | – | – | Hard-coded/(Reads) | Mapped reads |
Base qualities | Reads | Mapped reads | Reads | Reads | Mapped reads |
Sequence qualities | – | – | - | – | Mapped reads |
Substitution errors | Hard-coded | Mapped reads | Hard-coded | Reads | Mapped reads |
Systematic errors | – | – | – | – | Mapped reads |
InDel errors | Parameters | Mapped reads | Hard-coded | Reads | Mapped reads |
Variants | – | Two genomes | Vcf | – | Vcf |