Fig. 7

Overall method ranking based on 5 evaluation criteria. Average normalized ranks range from 0 to 1, lower values correspond to better performances. The type I error columns are based on the analysis of the 1000 mock comparisons from HMP 16S and WMS Stool datasets; the concordance analysis column is based on the average WMC values across the 100 random subset comparisons for each of the 6 datasets used. The power enrichment analysis and computational time columns are based on the Supragingival vs. Subgingival Plaque 16S dataset evaluations. Each method’s ordering is computed using the first 4 columns. Since the type I error analysis was not available for songbird and mixMC, these methods were not included in the final ranking