Fig. 1

Power and false positive rate for the MWAS methods in simulation scenario 1. The phenotypes were simulated based on the effects from 100 causal probes but no direct effects from the CTCs. a Mean genomic inflation factor from a method across 100 simulation replicates with an error bar representing ± SE of the mean. The dashed line at 1 shows the expected value if there is no inflation. b Box plot of AUCs for each method from 100 simulation replicates