Fig. 1From: Bazam: a rapid method for read extraction and realignment of high-throughput sequencing dataDifferent configurations for using Bazam. a Simple realignment from one reference genome to another without intermediate storage or steps. b Extraction of filtered reads such as those overlapping a specific locus. Reads can be streamed to downstream tools directly, or stored in FASTQ format for further processing. c Sharded realignment allows for many copies of the aligner to run on different subsets of the data, greatly speeding up realignmentBack to article page