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Fig. 4 | Genome Biology

Fig. 4

From: Genomes reveal marked differences in the adaptive evolution between orangutan species

Fig. 4

Adaptive history of the genus Pongo as inferred from codon modeling (MCM). Interaction networks of all genes under positive selection according to MCM in Northeast Bornean a and North Sumatran b individuals, generated using GeneMania (v3.4.0) in Cytoscape (v3.3.0) [97]. Each node in the network is a candidate gene identified through the selection test. Genes are labeled with their HUGO Gene IDs. We assigned putative functional classes (fill color) to genes according to the presence of specific keywords (Additional file 1: Table S9) in the GeneCards encyclopedia [51]. Gene interactions are shown by colored lines. The size of gene nodes reflects the number of interaction partners (edges) in the network

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