Fig. 8From: Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in humanPossible mechanisms for DNA secondary structure mediation of promoter-proximal Pol II pausing. The transcription complex (green) could be paused via multiple mechanisms: (1) by a secondary structure formed on the non-template strand of DNA itself; (2) by a protein recognizing such a structure; or (3) by an RNA:DNA hybrid (red and black lines)Back to article page