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Fig. 3 | Genome Biology

Fig. 3

From: Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human

Fig. 3

Pol II occupancy signals from Pol II ChIP-seq, GRO-seq, and NET-seq strongly correlate with stable DNA secondary structures of paused genes. Heat map representations of Pol II ChIP-seq (red), GRO-seq (blue), NET-seq (green) coverage and free energy (green-red) profile in HeLa-S3 cells are shown at the TSS ± 2 knt region. Paused genes (n = 11,019) were ordered by the distance of the Pol II ChIP-seq peak summit from each gene’s TSS

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Genome Biology

ISSN: 1474-760X

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