Table 2 The RNA-binding protein motifs associated with alternative exons that are coupled to TSS, other alternative exons, or PAS
R1 domain | ||||||
Motif | Length | Coupled (28,716) | Not coupled (70,336) | E-value | Pfam ID | RBP |
SVGV | 4 nt. | 12,121 | 23,872 | 6.0E-127 | PF00536 | SAMD4A |
TGTCTGAA | 8 nt. | 108 | 70 | 1.2E-014 | PF00076 | RBM24; ENOX1 |
R2 domain | ||||||
Motif | Length | Coupled (53,490) | Not coupled (131,953) | E-value | Pfam ID | RBP |
GSSB | 4 nt. | 29,261 | 65,661 | 2.4E-078 | PF00076; PF00098 | RBM4B |
GGGAYTAC | 8 nt. | 223 | 164 | 2.8E-027 | PF00013 | NOVA2 |
AGTMGCT | 7 nt. | 262 | 234 | 2.8E-024 | PF00076 | RBM28 |
R3 domain | ||||||
Motif | Length | Coupled (28,591) | Not coupled (70,138) | E-value | Pfam ID | RBP |
SGTRAG | 6 nt. | 1043 | 1330 | 7.6E-051 | PF00076; PF00641 PF00013 | FUS; SRSF2 PCBP1; PCBP2 |
GAAGGTGA | 8 nt. | 98 | 49 | 1.5E-016 | PF00076; PF00641 | RBM5 |