Fig. 6
From: Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
Prediction of double-strand breaks (DSBs) using a random forest learned from DSBs in one cell type (NHEK) to predict DSBs in another cell type (U2OS). a Receiver operating characteristic (ROC) curve to predict U2OS DSBs using the NHEK-learned random forest. Area under the ROC curve (AUROC) is plotted. b Variable importance from the prediction of U2OS DSBs using the U2OS-learned random forest. c Average profiles of DSBCapture, BLESS, XRCC4, and γ-H2AX at predicted DSB regions compared to non-DSB regions over the whole genome. AUROC area under the ROC curve, DSB double-strand break, ROC receiver operating characteristic