Fig. 2
From: Editing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome
The EIE of GluA2 can induce editing at the IM site in Gabra-3. a The wild-type Gabra-3 construct (G3 I/M) showing the short stem structure formed at the edited I/M site (red dot) and the EIE (in grey); the G3 I/M-ΔEIE mutant were the EIE has been deleted; and G3 I/M-DS GA2 EIE were the Gabra-3 EIE is replaced by the GluA2 EIE. b Quantification of editing efficiency at the I/M site in the different G3I/M constructs transfected into HeLa cells. c Quantification of editing efficiency at I/M site from the different G3I/M constructs when co-transfected with ADAR1 or ADAR2 in HEK293 cells. The mean value of the ratio between the A and G peak heights from three separate experiments was calculated as percentage editing. Error bars are standard deviation