Fig. 6
From: Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance
a The performance of ProGENI-SVR with different networks compared to PCC-SVR using all 24 treatments in the LCL dataset. The color blue in each bar chart represents the number of drugs for which the ProGENI-SVR performed better than the PCC-SVR (PIF >55%), while the color red shows the number of drugs for which the trend was opposite (PIF <45%). b The performance of predicting drug sensitivity of the test sets in the LCL dataset using 500 features selected by ProGENI using the LCL dataset (within-dataset) and the GDSC dataset (cross-dataset). The box plot shows the distribution of the SPCI values for each drug