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Table 5 Multivariate model that regresses epigenetic age acceleration on participant characteristics in the Bogalusa study. Coefficients and p values from regressing measures of intrinsic and extrinsic epigenetic age acceleration on participant characteristics from dataset 2

From: An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

Multivariate linear regression

Intrinsic EAA

Extrinsic EAA

  

Estimate (SE)

Z

p

Estimate (SE)

Z

p

Race

Caucasian vs. African American

–0.013 (0.316)

–0.04

0.97

0.843 (0.316)

2.67

0.0076

Gender

Female vs. Male

–0.622 (0.278)

–2.24

0.025

–0.718 (0.277)

–2.60

0.0093

Education

Grade 8–9 vs. < Grade 8

1.583 (1.468)

1.08

0.28

2.177 (1.465)

1.49

0.14

 

Grade 10–12 vs. < Grade 8

1.285 (1.27)

1.01

0.31

2.267 (1.267)

1.79

0.074

 

Vocat/Tech vs. < Grade 8

0.307 (1.299)

0.24

0.81

1.921 (1.295)

1.48

0.14

 

College vs. < Grade 8

0.85 (1.281)

0.66

0.51

2.375 (1.277)

1.86

0.062

 

Graduate vs. < Grade 8

0.147 (1.336)

0.11

0.91

1.53 (1.332)

1.15

0.25

Diabetes (II)

 

0.173 (0.485)

0.36

0.72

0.012 (0.483)

0.03

0.98

Hypertension

 

0.539 (0.291)

1.86

0.064

1.247 (0.29)

4.30

1.7 × 10-5

R-squared

 

0.025

  

0.043