Table 1 Overview of the DNA methylation datasets. The rows correspond to the datasets used in this article. Columns report the tissue source, DNA methylation platform, number of participants, access information, and citation and a reference to the use in this text
From: An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
Tissue source | Array | Participants (n) | Women (n) | African Ancestry, Caucasian, Hispanic, Tsimane, East Asian (n) | Mean age (years) (range) | Available | Citation | Figure |
|---|---|---|---|---|---|---|---|---|
1. Women’s Health Initiative (blood) | 450 | 1462 | 1462 | 676, 353, 433, 0, 0 | 63 (50–80) | dbGAP, NHLBI | Current article | 1 |
2. Bogalusa (blood) | 450 | 969 | 547 | 288, 681, 0, 0, 0 | 43 (29–51) | dbGAP, NHLBI | Current article | 1 |
3. PEG (blood) | 450 | 335 | 138 | 0, 289, 46, 0, 0 | 70 (36–91) | GSE72775 | Current article | 1 |
4. Saliva from PEG | 450 | 259 | 113 | 0, 166, 93, 0, 0 | 69 (36–88) | GSE78874 | Current article | 1 |
5. Older Tsimane and others | 450 | 310 | 150 | 0, 235, 38, 37, 0 | 66 (35–92) | GSE72773 | Current article | 3 |
6. Younger Tsimane and Caucasians | 450 | 46 | 31 | 0, 24, 0, 22, 0 | 15 (2–35) | GSE72777 | Current article | 3 |
7. East Asians vs. Caucasians (PSP samples removed) | 450 | 312 | 132 | 0, 279, 0, 0, 33 | 68 (34–93) | GSE53740 | Li, 2014 [73] | 3 |
8. African populations | 450 | 256 | 50 | 256, 0, 0, 0, 0 | 40 (16–90) | EGAS00001001066 | Fagny, 2015 [42] | 4 |
9. Cord blood | 27 | 216 | 110 | 92, 70, 0, 0, 0 | 0 (0–0) | GSE27317 | Adkins, 2011 [44] | |
10. Male saliva | 27 | 91 | 0 | 0, 59, 32, 0, 0 | 29 (21–55) | GSE34035 | Liu, 2010 [74] | |
11. Female saliva | 27 | 42 | 42 | 0, 27, 15, 0, 0 | 27 (21–55) | GSE34035 | Liu, 2010 [74] | |
12. Lymphoblastoid cell lines | 450 | 237 | 154 | 75, 68, 0, 0, 94 | 34 (5–73) | GSE36369 | Heyn, 2013 [88] | Additional file 1 |