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Fig. 7 | Genome Biology

Fig. 7

From: Fast and accurate single-cell RNA-seq analysis by clustering of transcript-compatibility counts

Fig. 7

Analysis on transcript-compatibility counts refines the classification of mouse brain cells. a Runs of affinity propagation with different propagation and damping parameters were carried out on the TCC matrix for the 3005 mouse brain cells of [7]. The Oligo3 subclass discovered by Zeisel et al. was consistently split into two subclasses A and B. b Cells in the Oligo3 B class showed greater expression of endothelial/vascular genes and lower expression of myelinating oligodendrocyte genes. The opposite was true for the cells in Oligo3 A. This result may corroborate the potential contamination of oligodendrocytes in the Zeisel et al. dataset that has recently been reported in Fan et al. [37]

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