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Table 1 Number of features (genes plus gene complexes), the number of genes covered by any of the features (# incl. genes), the number of counting bins, and the sum of all bin counts for various counting methods and for the complete and reduced annotation catalog. Randomly excluding 20 % of the transcripts from the annotation catalog generally led to a slight increase in the average bin count, with the most pronounced effects seen for the methods defining the counting bins as (combinations of) transcripts (kallisto and MISO). MISO and SplicingGraph consider only genes with at least two isoforms, which explains the lower number of features for these methods (Continued)

From: Isoform prefiltering improves performance of count-based methods for analysis of differential transcript usage

kallisto

# features

13,937

12,138

20,410

19,552

 

# incl. genes

13,937

12,138

20,410

19,552

 

# bins

26,951

21,561

145,342

116,274

 

Tot count

23,734,377

21,363,780

37,908,846

35,073,753

 

Tot count/# bins

880.65

990.85

260.83

301.65