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Fig. 3 | Genome Biology

Fig. 3

From: Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation

Fig. 3

Impact of confounding sequence variants on differential methylation and percentage of population differentially methylated CpGs (pDMCs) on total CpGs. a Significant DMCs (Fisher’s exact test p < 0.05) determined in filtered blacklisted region-removed but SNP-containing datasets were overlapped with dbSNP137-annoated variants for all samples. Shown is the percentage of DMCs overlapping with annotated SNPs in indicated differential methylation increments. b The bar plot displays the percentage of pDMCs on total detected CpGs for adipose and blood in variant-removed datasets. Shared pDMCs are indicated in purple

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Genome Biology

ISSN: 1474-760X

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