Figure 8
From: Domain atrophy creates rare cases of functional partial protein domains
Downstream domain-bounded atrophy: RNase E large domain. The E. coli RNase E large domain bound to a single strand RNA (yellow) (PDB: 2C0B). The large domain comprises four different sub-domains. The atrophied region of P. furiosus RNase E large domain (orange, residues 339-393), inferred through sequence mapping, corresponds to nearly half of the DNase I sub-domain. The active site residues involved in cleaving RNA are shown as sticks (grey) coordinating a Magnesium ion. Missing loop regions are represented as dashed lines.