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Figure 6 | Genome Biology

Figure 6

From: DGEclust: differential expression analysis of clustered count data

Figure 6

Comparison of ROC curves from different methods. The methods are applied to RNA-seq or CAGE data from a number of different species. In all cases, a ground truth was established by considering the absolute value of the log2 ratio of the mean expression across all replicas between two conditions [52]. DGEclust demonstrates excellent performance in all cases. At small sample sizes (n=2), it is ranked at the top, while for larger sizes (n=3 or n=5), it performs similarly to edgeR. CAGE, cap analysis of gene expression; RNA-seq, RNA sequencing; ROC, receiver operating characteristic.

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