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Figure 1 | Genome Biology

Figure 1

From: DNA-protein interactions in high definition

Figure 1

ChIP-exo protocol. The protocol utilizes adapter ligation and lambda exonuclease while the DNA is still crosslinked to the protein. After elution of the DNA and creation of double-stranded DNA (dsDNA), a unique adapter is ligated to the other end, thereby marking the 5' ends of the DNA-protein interactions. dsDNA, double-stranded DNA; TF, transcription factor.

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Genome Biology

ISSN: 1474-760X

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