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Table 2 Multiple regression models for expression divergence in duplicate genes

From: Coding region structural heterogeneity and turnover of transcription start sites contribute to divergence in expression between duplicate genes

Predictors

P-value

RCVE*

Cis†

4.2 × 10-2 (NS‡)

0.075

TSS§

9.9 × 10-5

0.277

Tandem¶

2.7 × 10-6

0.405

K A × Cis

1.1 × 10-2 (NS)

0.118

K S × Cis

2.7 × 10-2 (NS)

0.088

Structure¥ × Tandem

1.7 × 10-3

0.180

TSS × Tandem

1.1 × 10-5

0.354

ω# × Cis

3.1 × 10-3

0.159

R2

 

0.093

  1. *RCVE: relative contribution to the variability explained (see Materials and methods for more details). †Cis: divergence of cis-regulatory sequences in 2 kb surrounding TSS (see Materials and methods for more details). ‡NS: not significant after Bonferroni correction for multiple tests. §TSS: shared versus not shared TSSs. ¶Tandem: tandem versus nontandem organization of duplicate genes. ¥Structure: structural heterogeneity in coding sequences. #ω:K A /K S ratio.