Table 7 Categories for expert classification of novel predictions

A

Known true

There is experimental evidence for this annotation, but it is not yet captured by SGD (all supporting literature pre-dates the analysis)

B

Likely true

No experimental evidence exists in the literature, but there is author speculation or sequence similarity support for this annotation

C

Unclear

Experimental evidence is either unavailable or conflicting.

D

Unlikely

The gene product is known to have a related but different function/process and no experimental support was found for the prediction

E

Highly unlikely

Direct experimental evidence against this association, or all other experimental evidence supports an unrelated function/process, or the gene product is part of a well-characterized complex and the predicted component term was to a different well-characterized complex