Table 1 Mouse SuperArray data showing greater than twofold cell cycle RNA expression changes in the cerebellum of Wld^smice compared with wild-type controls

V-abl Abelson murine leukemia oncogene 1

Abl1

NM_009594

A01

21.91

1.74

Regulation

Cyclin B1

Ccnb1

NM_172301

A12

5.50

0.65

M phase and regulation

Antigen identified by monoclonal antibody Ki 67

Mki67

XM_133912

D09

4.23

0.41

S phase and DNA replication

Cyclin A2

Ccna2

NM_009828

A11

3.85

0.65

Regulation

G protein-coupled receptor 132

Gpr132

NM_019925

C11

3.73

0.82

G₁ phase and G₁/S transition

Checkpoint kinase 1 homolog

Chek1

NM_007691

C01

2.74

0.81

G₂ phase and G₂/M transition

Transformation related protein 63

Trp63

NM_011641

G10

2.53

0.06

Negative regulator

Cyclin-dependent kinase 2

Cdk2

NM_016756

B07

2.43

0.52

M phase

Calcium/calmodulin-dependent protein kinase II, beta

Camk2b

NM_007595

A08

2.41

0.10

G₁ phase and G₁/S transition

S-phase kinase-associated protein 2 (p45)

Skp2

NM_013787

F12

2.40

0.26

G₁ phase and G₁/S transition and regulation

Wee 1 homolog

Wee1

NM_009516

G12

2.33

0.02

M phase

Meiotic recombination 11 homolog A

Mre11a

NM_018736

D10

2.28

0.57

S phase and DNA replication

CDC28 protein kinase 1b

Cks1b

NM_016904

C02

2.23

0.49

Checkpoint and arrest and regulation

Breast cancer 2

Brca2

NM_009765

A06

2.23

0.63

M phase and regulation and checkpoint and arrest

Cyclin C

Ccnc

NM_016746

B02

2.07

0.12

regulation

Transcription factor Dp 1

Tfdp1

NM_009361

G07

2.07

0.06

Regulation

SMT3 suppressor of mif two 3 homolog 1

Sumo1

NM_009460

G04

2.04

0.13

S phase and DNA replication

Retinoblastoma-like 2

Rbl2

NM_011250

F08

2.01

0.25

Negative regulator