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Figure 4 | Genome Biology

Figure 4

From: An improved method for detecting and delineating genomic regions with altered gene expression in cancer

Figure 4

Application to synthetic data. For illustration, we applied the different methods to a large set of synthetic examples. Left: Original gene expression bias profile. Middle: Results for proposed method. Right: Results for CGHseg. As evident, the proposed method better succeeds in recovering the true expression bias profile, especially under rough conditions. The example shown was generated using π = 0.2, but agreeing results were obtained for π = 0.0 to 0.5. In this test, T μ = 0.5·SNR (similar results for other reasonable values).

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