| Site e1* | Site e2* | Site e3* | Site e4* | Site e5* |
---|
SF2/ASF†|  | CACACCT (3.2/3.6) |  |  | CTCAGGA (4.8/NA) |
SC35†|  |  | AATCACAG (NA/4) | AATCACAG (NA/2.6) |  |
SRp40†|  | GCACACC (2.6/NA) |  |  | CTACTCA (NA/5.1) |
 |  |  |  |  | ACTCAGG (4.2/NA) |
SRp55†|  | TGCACA (NA/3.1) |  |  |  |
Ast‡ | AGTGCA§ |  |  |  | TCAGGA |
Burge¶¥ | TGGTGG |  |  |  | GGGAGG |
 | GGTAGT |  |  |  | TCAGGA |
hnRNP F | Â | Â | Â | Â | GGGA |
- The sequence of the exonic splicing regulatory sequence is shown. The edited 'A' nucleotide is in bold (unless otherwise indicated). The numbers in parentheses indicate the binding score before/after editing; NA indicates no available score. *Edited sites: E1, position 19 in the Alu-exon; E2, position 24; E3, position 32; E4, position 33; E5, position 46. †Predicted by ESEfinder [31]. ‡Predicted by Goren et al. [28]. §This unedited ESR overlaps with both E1 and E2 sites. ¶Predicted by RESCU-ESE [30]. ¥Sites E1 and E5 created two different hexamers for the edited and unedited position, according to RESCU-ESE [30].