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Table 1 CDK target sets used in this study

From: Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

Set Ascertainment Total Definition of target Positives
'Known' Unknown, complex 12 Low-throughput experimental characterization 12
'Unbiased' randomly chosen proteins 198 Score > 2 in high-throughput assay 18
'2+' All S. cerevisiae proteins containing two or more matches to the 'strong' CDK consensus 385 Score > 2 in high-throughput assay 143
'1cc' All S. cerevisiae proteins containing one match to the 'strong' CDK consensus and exhibiting cell cycle regulated transcription 137 Score > 2 in high-throughput assay 32
  1. Four cyclin-dependent kinase (CDK) target sets from Saccharomyces cerevisiae [11]. Note that only the high-throughput data contain 'negatives'. The 'strong' CDK consensus is S/T-P-X-R/K, where X represents any amino acid.