Figure 5

Paralogs. Fraction of proteins, that is, party hubs (PHs), date hubs (DHs) and non-hubs (NHs), that have paralogs, inparalogs (i.e. paralogs that have been duplicated after the split between S. cerevisiae and S. pombe) and ohnologs (paralogs resulting from the whole genome duplication). In DIP, the fraction of party hub inparalogs is small, approximately 0.2 compared to approximately 0.4 for the other connectivity groups (P value <10^-5), and so is the fraction of ohnologs for party hubs compared to the other groups (P value <10^-5). The results in the FYI data set are similar, although the fraction of date hub paralogs is smaller than in the DIP data set.