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Table 1 Correlation between enzymatic flux magnitude and evolutionary constraint Ka/Ks

From: Influence of metabolic network structure and function on enzyme evolution

Uptake Maximum uptake rates (mmol/gDW/h) Spearman's rank correlation (P value) with zero fluxes Spearman's rank correlation (P value) without zero fluxes
Glucose/oxygen 15.3/2.4 -0.28 (P = 3.8 × 10-3) -0.25 (P = 3.6 × 10-6)
Glucose/oxygen 15.3/0.2 -0.31 (P = 1.7 × 10-3) -0.22 (P = 5.7 × 10-5)
Glucose/oxygen 15.3/0.01 -0.26 (P = 9.3 × 10-3) -0.21 (P = 1.2 × 10-4)
Fructose/oxygen 15.3/6.0 -0.27 (P = 6.4 × 10-3) -0.20 (P = 2.5 × 10-4)
Fructose/oxygen 15.3/0.2 -0.25 (P = 1.3 × 10-2) -0.20 (P = 1.8 × 10-6)
Acetate/oxygen 10.0/2.4 -0.08 (P = 0.45) -0.21 (P = 9.2 × 10-5)
Acetate/oxygen 5.0/5.0 -0.010 (P = 0.39) -0.19 (P = 3.7 × 10-4)
  1. The correlation between enzymatic flux magnitude and evolutionary constraint Ka/Ks was calculated with and without enzymes carrying zero fluxes. gDW, grams dry weight.