Table 1 Selenoprotein families identified in the Sargasso Sea database
Prokaryotic selenoprotein family | Unique sequences | COG/Pfam ID | COG/Pfam description |
|---|---|---|---|
Known selenoproteins (209 sequences) | |||
SelW-like protein | 48 | Pfam05169 | Selenoprotein W-related |
Peroxiredoxin (Prx) | 43 | COG1225 | Peroxiredoxin |
Proline reductase (PrdB) | 42 | - | Â |
Selenophosphate synthetase | 28 | COG0709 | Selenophosphate synthetase |
Prx-like protein | 22 | COG0450 | Peroxiredoxin-like |
Thioredoxin (Trx) | 11 | COG3118 | Thioredoxin |
Formate dehydrogenase alpha chain (fdhA) | 8 | COG0243 | Anaerobic dehydrogenases |
Glutathione peroxidase (GPx) | 5 | COG0386 | Glutathione peroxidase |
Glycine reductase selenoprotein A (grdA) | 1 | - | Â |
Glycine reductase selenoprotein B (grdB) | 1 | Pfam07355 | Glycine reductase selenoprotein B |
New selenoproteins (101 sequences) | |||
AhpD-like protein | 27 | COG2128 | Uncharacterized conserved protein |
Arsenate reductase | 14 | COG1393 | Arsenate reductase and related proteins |
Molybdopterin biosynthesis MoeB protein | 11 | COG0476 | Dinucleotide-utilizing enzymes, molybdopterin biosynthesis |
Glutaredoxin (Grx) | 10 | COG0695 | Glutaredoxin and related proteins |
DsbA-like protein | 9 | COG2761 | DsbA-like |
Glutathione S-transferase | 4 | COG0625 | Glutathione S-transferase |
Deiodinase-like protein | 4 | Pfam00837 | Iodothyronine deiodinase |
Thiol-disulfide isomerase-like protein | 4 | - | Â |
CMD domain-containing protein | 4 | Pfam02627 | Carboxymuconolactone decarboxylase |
Hypothetical protein 1 | 4 | - | Â |
Rhodanese-related sulfurtransferase | 3 | COG2897 | Rhodanese-related sulfurtransferase |
OsmC-like protein | 3 | COG1765 | Predicted redox protein, OsmC-like |
DsrE-like protein | 2 | Pfam02635 | DsrE-like |
DsbG-like protein | 1 | COG1651 | DsbG, Protein-disulfide isomerase |
NADH:ubiquinone oxidoreductase | 1 | COG2209 | NADH:ubiquinone oxidoreductase |
Total | 310 | Â | Â |