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Table 6 Pathways (including superpathways) that are common to human, bacteria and plant PGDBs

From: Computational prediction of human metabolic pathways from the complete human genome

Class

Subclass

Pathway

Biosynthesis

Polyamines

Betaine biosynthesis

  

Polyamine biosynthesis

 

Fatty acids and lipids

Phospholipid biosynthesis

  

Fatty acid biosynthesis - initial steps

  

Fatty acid elongation - saturated

 

Cofactors, prosthetic groups, electron carriers

Pyridine nucleotide biosynthesis

  

Thioredoxin pathway

  

Glutathione biosynthesis

  

Pantothenate and coenzyme A biosynthesis

  

Pyridoxal 5'-phosphate salvage pathway

  

Polyisoprenoid biosynthesis

  

FormylTHF biosynthesis

 

Cell structures

Colanic acid building blocks biosynthesis

  

GDP-mannose metabolism

 

Carbohydrates

Gluconeogenesis

  

Trehalose degradation - low osmolarity

 

Aminoacyl-tRNAs

tRNA charging pathway

 

Amino acid biosynthesis

Proline biosynthesis I

  

Glycine biosynthesis I

  

Serine biosynthesis

Degradation

Sugars and polysaccharides

Glucose 1-phosphate metabolism

  

Galactose metabolism

  

Trehalose degradation - low osmolarity

  

Glycogen degradation

  

Ribose degradation

 

Other degradation

Removal of superoxide radicals

 

Nucleosides and nucleotides

(Deoxy)ribose phosphate metabolism

 

Fatty acids

Fatty acid oxidation pathway

 

Carboxylates, other

Acetate degradation

 

Amino acids, amines

L-serine degradation

 

Alcohols

Glycerol metabolism

Energy metabolism

 

Pyruvate dehydrogenase

  

TCA cycle - aerobic respiration

  

Glycolysis

  

Oxidative branch of the pentose phosphate pathway

  

Nonoxidative branch of the pentose phosphate pathway

  1. HumanCyc, H. sapiens; EcoCyc, E. coli; AraCyc, A. thaliana. The pathways in the table are included in all three PGDBs.