Figure 3
From: Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes
Median KA/KS ratios for rat and mouse orthologs of human disease genes. Median KA/KS values for each disease category are depicted for rat (color) and mouse (grey) demonstrating differences by disease category. The disease categories exhibiting the greatest purifying selection, the neurological and malformation-syndrome disease systems, show the lowest median KA/KS ratios.