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Table 4 Summary of the number of functional linkages between M. tuberculosis genes established by each of the four prediction methods of this paper, alone and in combination

From: Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach

Method(s)

Functional links

Proteins

One method

  

Rosetta Stone

20,714

1,279

Gene Neighbor

15,550

1,658

Phylogenetic Profiles

67,684

1,815

Operon (≤100 bp)

8,468

2,870

Two methods

  

100 bp Operon and RS

414

 

100 bp Operon and PP

632

 

100 bp Operon and GN

1516

 

Three methods

  

100 bp Operon, RS and PP

186

 

100 bp Operon, RS and GN

246

 

100 bp Operon, PP and GN

472

 

All four methods

  

100 bp Operon, PP, GN and RS

138

 
  1. PP, Phylogenetic Profile method; GN, conserved Gene Neighbor method; RS, Rosetta Stone method.
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Genome Biology

ISSN: 1474-760X

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